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339 Toll-like receptor mediated innate immune response in hepatocytes suppressed woodchuck hepatitis virus replication via interferon-independent pathway

✍ Scribed by Xiaoyong Zhang; Zhongji Meng; Yang Xu; Jörg Schlaak; Michael Roggendorf; Mengji Lu


Book ID
116398639
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
47 KB
Volume
43
Category
Article
ISSN
1043-4666

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We have previously shown that Toll-like receptor (TLR)-activated murine nonparenchymal liver cells [(NPC); Kupffer cells (KC), liver sinusoidal endothelial cells (LSEC)] can suppress hepatitis B virus (HBV) replication. Therefore, the aim of this study was to investigate whether HBV has the ability