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336 VEGF and angiopoietin-1 as hypoxia-inducible, autocrine and paracrine chemotactic factors for human hepatic stellate cells

✍ Scribed by E. Novo; S. Cannito; E. Zamara; L. Valfrè di Bonzo; A. Caligiuri; S. Colombatto; E. Marra; M. Pinzani; M. Parola

Book ID
117374615
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
136 KB
Volume
44
Category
Article
ISSN
0168-8278

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Following liver injury, hepatic stellate cells (HSC) undergo proliferation and migrate into damaged areas in response to chemotactic factors. HSC have been shown to regulate leukocyte trafficking by secreting monocyte chemotactic protein-1 (MCP-1), a chemokine that recruits monocytes and lymphocytes