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3,3′-Diindolylmethane and Paclitaxel Act Synergistically to Promote Apoptosis in HER2/Neu Human Breast Cancer Cells

✍ Scribed by K.P. McGuire; N. Ngoubilly; M. Neavyn; S. Lanza-Jacoby

Book ID: 116702586
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 691 KB
Volume: 132
Category: Article
ISSN: 0022-4804
DOI: 10.1016/j.jss.2006.02.008

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## Abstract Constitutive activation of the Wnt pathway as a result of __APC__, __AXIN1__ or __CTNNB1__ mutations has been found in most colorectal cancers. For a long time, this aberrant Wnt activation has been thought to be independent of upstream signals. However, recent studies indicate that ups