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32P-Postlabeling Analysis of DNA Adducts in Rats during Estrogen-induced Hepatocarcinogenesis and Effect of Tamoxifen on DNA Adduct Level

✍ Scribed by Shimomura, Makoto ;Higashi, Shunsaku ;Mizumoto, Ryuji


Book ID
108579465
Publisher
Wiley (Blackwell Publishing)
Year
1992
Tongue
English
Weight
517 KB
Volume
83
Category
Article
ISSN
0910-5050

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P-Postlabeling is a widely applied assay for the analysis of carcinogen-DNA adducts. Optimization of most steps in this assay has been given attention, but influences of DNA isolation and DNA purity on adduct quantitation have not been investigated systematically. In this study, DNA was isolated fro