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326 Assessment of the Efficacy and Safety of Certolizumab Pegol for the Treatment of Moderate to Severe Ulcerative Colitis

✍ Scribed by Scott D. Lee; Mark T. Osterman; Susan C. Parrott; Chelle L. Wheat


Book ID
119433130
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
75 KB
Volume
142
Category
Article
ISSN
0016-5085

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Exogenous alkaline phosphatase for the t
✍ Milan Lukas; Pavel Drastich; Michal Konecny; Paolo Gionchetti; Ondrej Urban; Fra πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 109 KB

Background: Increased activity of intestinal alkaline phosphatase (AP) occurs locally in patients with ulcerative colitis (UC), aimed at repairing inflammatory tissue damage. We evaluated the safety and preliminary efficacy of exogenous AP administered to patients with UC in an open-label, first-in-