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325Antisense-mediated telomerase inhibition sensitizes human bladder cancer cell lines to chemotherapeutic drugs

✍ Scribed by K. Kraemer; S. Fuessel; U. Schmidt; A. Meye; M.P. Wirth


Book ID
118646457
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
180 KB
Volume
4
Category
Article
ISSN
1569-9056

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## Abstract We reported recently that roscovitine (ROSC), a selective cyclin‐dependent kinase (CDK) inhibitor, arrests human MCF‐7 breast cancer cells in G~2~ phase of the cell cycle, and concomitantly induces apoptosis. Human MCF‐7 breast cancer cells are known to express elevated levels of c‐Ha‐R