Proteolytic processing of the Alzheimer'
✍
Geneviève Evin; Aiqin Zhu; R.M. Damian Holsinger; Colin L. Masters; Qiao-Xin Li
📂
Article
📅
2003
🏛
John Wiley and Sons
🌐
English
⚖ 175 KB
👁 1 views
## Abstract Proteolytic processing of the amyloid precursor protein by β ‐and γ‐secretases results in the production of Alzheimer's disease (AD) Aβ amyloid peptides. Modulation of secretase activity is being investigated as a potential therapeutic approach. Recent studies with human brain have reve