[3+2] Cycloaddition reactions of ethyl (Z)-3-fluoropropenoate with nitrones
β Scribed by Patrick, Timothy B.; Khan, Akbar H.
- Book ID
- 123403785
- Publisher
- Elsevier Science
- Year
- 2013
- Tongue
- English
- Weight
- 314 KB
- Volume
- 155
- Category
- Article
- ISSN
- 0022-1139
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π SIMILAR VOLUMES
Ethyl 2-hydropoly(per)fluoroalk-2-enoates react readily with nitrones under mild conditions to give 5-fluoroalkyl substituted isoxazolidines as a mixture of two diastereoisomers (trans and cis) in high yields.
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The cycloaddition reaction of 2,4-dinitrophenylsulfinylpropadiene with several nitrones has been investigated. The initial 3+2-cycloadduct readily undergoes a subsequent 2,3sigmatropic rearrangement.