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31P-TMR studies of cardiotoxic effects of 5′-deoxy-5-fluorouridine (5′-DFUR) and 5-fluorouracil (5-FU)

✍ Scribed by H. Tamatsu; M. Nakazawa; S. Imai; H. Watari


Book ID
118915931
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
89 KB
Volume
15
Category
Article
ISSN
0022-2828

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A gas chromatography-mass spectrometry (GC-MS) method for the simultaneous determination of 5'-deoxy-Sfluorouridine (doxifluridine, 5'-dFUR), 5fluorouracil (5-FU) and its main catabolite 5,6-dihydro-5-fluorouracil (5-FUH\*) in human plasma has been developed. Sample preparation consisted of protein