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31P localized spectroscopy of fetal brain in utero

✍ Scribed by Tsutomu Nakada; Ingrid L. Kwee

Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
285 KB
Volume
29
Category
Article
ISSN
0740-3194

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✦ Synopsis

Abstract

31‐Phosphorus (^31^P) nuclear magnetic resonance (NMR) spectroscopy of fetal brain in utero was obtained entirely noninvasively in rat utilizing image selected in vivo spectroscopy (ISIS). The results were in excellent agreement with the data obtained using the surface coil method in the late stage fetus, namely, high phosphomonoester (PME), low phosphocreatine (PCr), and high intracellular pH. Localized spectroscopy provides unprecedented opportunities for the investigation of fetal brain metabolism in utero.

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