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316. Secretion of oestradiol-17β and proteins by isolated Sertoli cells: effects of serum and incubation temperature

✍ Scribed by F.F.G. Rommerts; J.A. Grootegoed; F.H. De Jong; H.J. Van Der Molen


Book ID
116001348
Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
156 KB
Volume
9
Category
Article
ISSN
0022-4731

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✍ Eric F. Adams; B. Rafferty; M. C. White 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 French ⚖ 472 KB

## Abstract Previous studies have demonstrated that cultured human breast fibroblasts secrete a high‐molecular‐weight polypeptide which stimulates the ability of human breast‐cancer MCF‐7 cells to convert oestrone (E1) to the biologically more active 17β‐oestradiol (E2). This effect is mediated by