Basic science reviews: Oncogenes
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Dr. Norris K. Lee
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Article
📅
1992
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John Wiley and Sons
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English
⚖ 879 KB
Currently, the most widely accepted paradigm of oncogenesis is based on the concept of a balance between positive-and negative-growth regulatory mechanisms. Aberrations in these regulatory pathways can lead to a transformed phenotype, seen clinically as tumorigenesis. In vivo, there may be additiona