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3.040 ASSOCIATION OF INTRON RS12138592 A/G POLYMORPHISM OF UBIQUITIN SPECIFIC PROTEASES (USP24) GENE WITH PARKINSON DISEASE

✍ Scribed by Z. Lin

Book ID: 117755143
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 56 KB
Volume: 18
Category: Article
ISSN: 1353-8020
DOI: 10.1016/s1353-8020(11)70776-3

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## Monoamine oxidase B (MAO -B ) is an enzyme that has relevance for Parkinson disease (PD) because of its roles in catabolizing dopamine and potentially activating exogenous neurotoxicants. A polymorphism of the gene encoding MAO-B has been identified as a single base change (A or G) in intron