3.017 ASSOCIATION OF MUTATIONS IN THE GLUCOCEREBROSIDASE GENE WITH PARKINSON DISEASE IN A KOREAN POPULATION
โ Scribed by Y.J. Kim; J.M. Choi; W.C. Kim; C.H. Lyoo; S.Y. Kang; P.H. Lee; J.S. Baik; S.B. Koh; H.-I. Ma; Y.H. Sohn; M.S. Lee
- Book ID
- 117755121
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 60 KB
- Volume
- 18
- Category
- Article
- ISSN
- 1353-8020
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FIG. 1. MRI showed symmetric (A) hypointensity signal on T1weighted imaging and (B) hyperintensity signal on T2-weighted imaging in bilateral substantia nigra on admission. A repeated MRI after 3 months showed resolution of the lesions on (C) T2-weighted imaging and (D) T1-weighted imaging.
## Abstract Recent studies have reported an association between the glucocerebrosidase (__GBA__) gene and Parkinson's disease (PD). To elucidate the role of this gene in our population, we screened 395 PD patients and 483 controls from southern Italy for the N370S and the L444P mutations. We found