[3.01] 3-D intraoperative imaging combining an operating microscope with optical coherence tomography (OCT)
✍ Scribed by Eva Lankenau; David Klinger; Heike Hedwig Müller; Asim Malik; Christian Winter; Alf Giese; Stefan Oelckers; Tino Just; Gereon Hüttmann
- Book ID
- 104056587
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 57 KB
- Volume
- 24
- Category
- Article
- ISSN
- 1615-1615
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✦ Synopsis
Objective: Optical coherence tomography (OCT) allows non-contact/non-invasive analysis of tissues with a penetration depth of 2-3 mm reaching a spatial resolution of approximately 4-15 mm. This resolution is compatible with the resolution of modern operation microscopes. Aim of this work was to provide a three-dimensional (3D) intraoperative visualization of tissue structures. Material and methods: A high-speed spectral-domain OCT (a modified version of the Ganymed, Thorlabs HL) was adapted to a motorized operation microscope (HR 1000, Mo ¨ller-Wedel). Via a specially designed two axisscanner, the 840 nm OCT was adapted directly to a camera port of the operation microscope. Group velocity dispersion of the microscope optics was compensated successfully to provide bandwidth-limited depth resolution. Together with a step motor-controlled reference arm, an automatic control of the working distance (232-290 mm), the scan field (4-24 mm) and the position of the OCT focus within the sample is possible. Results: The system allows a 3-D visualization of OCT imaged during the surgical procedure. The OCT images were provided to the surgeon via a special video ocular in the surgical microscope. This new device was tested successfully in a preclinical setting with different ENT tissues to evaluate the principle. Conclusion: It may be used during brain tumor surgery, tumor surgery of the vocal cords, the placement of cochlear transplants or during bone surgery in the middle ear.