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3-Pyrrolidinecarboxylic Acid for Direct Catalytic Asymmetric a nti -Mannich-Type Reactions of Unmodified Ketones

โœ Scribed by Zhang, Haile; Mifsud, Maria; Tanaka, Fujie; Barbas, Carlos F.


Book ID
118063813
Publisher
American Chemical Society
Year
2006
Tongue
English
Weight
52 KB
Volume
128
Category
Article
ISSN
0002-7863

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Direct catalytic asymmetric Mannich reac
โœ Shingo Yamasaki; Takehiko Iida; Masakatsu Shibasaki ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 603 KB

The direct catalytic asymmetric Mannich reaction of unmodified ketones is described. This was achieved by the cooperative catalysis of a heterobimetallic asymmetric complex: AILibis(binaphthoxide) (ALB) and La(OTf)3.nH,\_O in the presence of molecular sieves 3A. The association of ALB and La(OT0fnH2