## Abstract 3โPhosphoglycerate dehydrogenase (3โPGDH) deficiency is an inborn error of serine biosynthesis. Patients are affected with congenital microcephaly, psychomotor retardation, and intractable seizures. The effects of oral treatment with amino acids were investigated in 2 siblings. LโSerine
โฆ LIBER โฆ
3-Phosphoglycerate dehydrogenase deficiency and 3-phosphoserine phosphatase deficiency: Inborn errors of serine biosynthesis
โ Scribed by J. Jaeken; M. Detheux; L. Van Maldergem; J. P. Frijns; P. Alliet; M. Foulon; H. Carchon; E. Van Schaftingen
- Publisher
- Springer
- Year
- 1996
- Tongue
- English
- Weight
- 303 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0141-8955
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## Abstract Microglia are well known to become activated during various kinds of neuropathological events. The factors that are responsible for the activation, however, are not fully determined. In the present study, LโSer was shown to enhance production of nitric oxide (NO), interleukinโ6 (ILโ6) a