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3- O -Desacyl Monophosphoryl Lipid A Derivatives: Synthesis and Immunostimulant Activities †

✍ Scribed by Johnson, David A.; Keegan, David S.; Sowell, C. Gregory; Livesay, Mark T.; Johnson, Craig L.; Taubner, Lara M.; Harris, Annalivia; Myers, Kent R.; Thompson, Jennifer D.; Gustafson, Gary L.; Rhodes, Michael J.; Ulrich, J. Terry; Ward, Jon R.; Yorgensen, Yvonne M.; Cantrell, John L.; Brookshire, Valerie G.


Book ID
121470483
Publisher
American Chemical Society
Year
1999
Tongue
English
Weight
154 KB
Volume
42
Category
Article
ISSN
0022-2623

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Synthesis of a Monophosphoryl Derivative
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## Abstract Monophosphoryl lipid A is a safe and potent immunostimulant and vaccine adjuvant, which is potentially useful for the development of effective carbohydrate‐based conjugate vaccines. This paper presents a convergent and efficient synthesis of a monophosphoryl derivative of __E. coli__ li