3-Hydroxy-1-(3-imidazolylpropyl)-2-methyl-4-pyridinone dihydrochloride dihydrate
✍ Scribed by Burgess, John ;Fawcett, John ;Parsons, Simon A.
- Publisher
- International Union of Crystallography
- Year
- 2001
- Tongue
- English
- Weight
- 191 KB
- Volume
- 57
- Category
- Article
- ISSN
- 1600-5368
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📜 SIMILAR VOLUMES
Single-crystal X-ray study T = 183 K Mean '(C±C) = 0.002 A Ê Disorder in main residue R factor = 0.049 wR factor = 0.144 Data-to-parameter ratio = 16.2 For details of how these key indicators were automatically derived from the article, see http://journals.iucr.org/e.
The title compound, C 29 H 27 NO 7 , has a non-planar con®guration. The methoxycarbonylmethyl group exhibits an E con®guration. The crystal structure is stabilized by intermolecular OÐHÁ Á ÁO and CÐHÁ Á ÁO contacts.
The title compound, C 18 H 26 ClNO 2 , is one of a group of decahydroisoquinoline derivatives that are known to exhibit a diverse range of bioactivities. The piperidine and cyclohexanone rings exist in chair conformations and form a cisfused decalin-type bicyclic framework. In the crystal structure,