Organocatalyzed synthesis of 2-amino-8-o
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Derong Ding; Cong-Gui Zhao
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Article
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2010
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Elsevier Science
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French
⚖ 279 KB
2-Amino-8-oxo-tetrahydro-4H-chromene-3-carbonitriles were synthesized for the first time from a tandem Michael addition - cyclization reaction between cyclohexane-1,2-dione and benzylidenemalononitriles. An enantioselective synthesis of these compounds was achieved in moderate ee values (up to 63% e