3-(Diphenylmethoxy)-8-methyl-8-azoniabicyclo[3.2.1]octane methanesulphonate monohydrate (benztropine methanesulphonate monohydrate)
✍ Scribed by Jones, P. G. (author);Kennard, O. (author);Horn, A. S. (author)
- Book ID
- 114525509
- Publisher
- International Union of Crystallography (IUCr)
- Year
- 1978
- Weight
- 272 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0567-7408
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📜 SIMILAR VOLUMES
Geometric parameters of the title compound, C 10 H 14 NO 2 + Á-Cl À ÁH 2 O, are in the usual ranges. The tetrahydropyridine ring adopts a half-chair conformation with the methyl group in an equatorial and the hydroxy group in an axial position. The crystal packing is stabilized by O-HÁ Á ÁO, O-HÁ Á
The title compound, C~11~H~16~N~2~ ^2+^·2Cl^−^·H~2~O, is a novel conformationally constrained tricyclic analogue of nicotine, in which the pyridine and pyrrolidine rings of the latter are bridged by a CH~2~ group. As result of this bridge, these two rings are no longer approximately perpendicular as
The title compound, C 20 H 29 NO 3 ÁH 2 O, has been synthesized by the reaction of hydroxylamine with butyraldehyde and dimidone in ethylene glycol under microwave irradiation. The dihydropyridine ring adopts a boat conformation.