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3″-De-O-methyl-2″,3″-anhydro-lankamycin, a New Macrolide Antibiotic from Streptomyces violaceoniger

✍ Scribed by Jerry R. Martin; Richard S. Egan; Alma W. Goldstein; Sandra L. Mueller; Walter Keller-Schierlein; Lester A. Mitscher; Rodger L. Foltz


Book ID
102251550
Publisher
John Wiley and Sons
Year
1976
Tongue
German
Weight
491 KB
Volume
59
Category
Article
ISSN
0018-019X

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✦ Synopsis


Abstract

A further examination of the products from fermentation broths of Streptomyces violaceoniger has yielded small quantities of several lankamycin related antibiotics and metabolites. One of the antibiotics has been characterized as 3″‐de‐O‐methyl‐2″,3″‐anhydro‐lankamycin. The anhydro sugar of the new lankamycin, 3‐methyl‐4‐O‐acetyl‐2,3,6‐trideoxy‐α‐L‐threo‐hex‐2‐enepyranoside was also isolated as the ethyl glycoside from fermentation broths of the same organism.