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3-C-Hydroxymethyl-D-riburonic Acid Synthesis of the Branched-Chain Uronic Acid and comparison with a carbohydrate component of a naturally occurring bilirubin conjugate

✍ Scribed by Walter P. Blackstock; Clive C. Kuenzle; Conrad H. Eugster


Book ID
102252755
Publisher
John Wiley and Sons
Year
1974
Tongue
German
Weight
478 KB
Volume
57
Category
Article
ISSN
0018-019X

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✦ Synopsis


Abstract

A novel carbohydrate has previously been isolated from human bile as a complex glycoside of bilirubin [1]. This compound has been tentatively identified as 3‐C‐hydroxymethyl‐D‐riburonic acid. To test this structural assignment the proposed branched‐chain uronic acid was synthesized. Gas chromatographic and mass spectrometric comparison of the natural and synthetic materials indicated that the proposed structure, 3‐C‐hydroxymethyl‐D‐riburonic acid, did not apply to thc natural product.