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3-Azabicyclo[3.3.1]nonane Derivatives: III. Synthesis of 3-Substituted 9-Acetonyl-1,5-dinitro-3-azabicyclo[3.3.1]-non-6-en-8-ones by Mannich Condensation of the Janovsky σ-Adduct of 2,4-Dinitrophenol with Acetonide Ion

✍ Scribed by O. V. Leonova; I. V. Shakhkel'dyan; Yu. D. Grudtsyn; Yu. M. Atroshchenko; E. N. Alifanova; S. S. Gitis; P. V. Chudakov; E. G. Nikiforova; N. N. Alekhina; A. Ya. Kaminskii


Book ID
110313624
Publisher
SP MAIK Nauka/Interperiodica
Year
2001
Tongue
English
Weight
50 KB
Volume
37
Category
Article
ISSN
1070-4280

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Reactions of 4-Oxoalkanoic Acids, 4. Syn
✍ Wedler, Christine ;Schick, Hans ;Scharfenberg-Pfeiffer, Doris ;Reck, Günter 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 432 KB

## Abstract Ethyl 4‐oxoalkanoates 1 react at ambient temperature in dry methanol in the presence of molecular sieve 3 Å in almost quantitative yield with 3‐aminopropanol and 2‐aminoethanol to form the bicyclic lactams __rac__‐2 and __rac__‐3, respectively. Surprisingly, the (±)‐5‐alkyl‐4‐oxa‐1‐azab