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3-Aryl-3-arylmethoxyazetidines. A new class of high affinity ligands for monoamine transporters

✍ Scribed by Thaxton, Amber; Izenwasser, Sari; Wade, Dean; Stevens, Edwin D.; Mobley, David L.; Jaber, Vivian; Lomenzo, Stacey A.; Trudell, Mark L.


Book ID
120510631
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
574 KB
Volume
23
Category
Article
ISSN
0960-894X

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The synthesis, receptor binding, and preliminary structural characterisation of trishomocubanes of types pentacyclo [5.4.0.02'6.03'lΒ°.05'9]undecylamines and 4-azahexacyclo[5.4.1.0E'6.03'lΒ°.05'9.08'll]dodecanes are described. These ligands demonstrated high selectivity and affinity for the sigma bind