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3-Aryl-2-methylserines III. Synthesis via alanine azlactone

โœ Scribed by Seemon H. Pines; Meyer Sletzinger


Book ID
104239120
Publisher
Elsevier Science
Year
1969
Tongue
French
Weight
75 KB
Volume
10
Category
Article
ISSN
0040-4039

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## Abstract A novel method for the synthesis of __N__โ€methylserines has been developed. The oxazolidines 4 are formed by condensation of the serine methyl esters 1 with formaldehyde. These intermediates are subsequently reduced to the __N__โ€methylserine methyl esters 9 by an acidโ€catalyzed ring ope