𝔖 Bobbio Scriptorium
✦   LIBER   ✦

3-Aminopyridine

✍ Scribed by Chao, M. ;Schemp, E. ;Rosenstein, R. D.


Book ID
117859913
Publisher
International Union of Crystallography
Year
1975
Weight
319 KB
Volume
31
Category
Article
ISSN
0567-7408

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Palladium-catalyzed cross-coupling of methylboronic acid with 2-chloro-3-nitropyridine produced 2methyl-3-nitropyridine 4 in one step in high yield. Oxidation of 4 with selenium dioxide gave aldehyde 5. Alternatively, condensation of 4 with DMFDMA followed by oxidation gave 5 in a two step higher yi