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3-Aminopiperid-2-one, an unusual metabolite in the urine of a patient with hyperammonaemia, hyperornithinaemia and homocitrullinuria

โœ Scribed by Vanessa Fell; Rodney J. Pollitt


Book ID
115822144
Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
324 KB
Volume
87
Category
Article
ISSN
0009-8981

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The identification of (E)-2-methylglutaconic acid, a 'new' metabolite of isoleucine, is described. The substance was detected in urine samples from patients with propionic acidaemia, methylmalonic acidaemia and so-called P-ketothiolase deficiency; in the majority of cases together with N-tiglylglyci