3. A randomized trial of the new specific aromatase inhibitor ‘Arimidex’ (anastrozole) versus megestrol acetate (MA) in the treatment of postmenopausal women with advanced breast cancer (ABC)
✍ Scribed by W. Jonat; A. Howell; C.P. Blomqvist; W. Eiermann; G. Winblad; C.J. Tyrrell; L. Mauriac; H. Roche; S. Lundgren; R. Hellmund; M. Azab
- Book ID
- 113404511
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 435 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0960-9776
No coin nor oath required. For personal study only.
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The trial was randomized, double blind for anastrozole, open label for for the Arimidex Study Group megestrol acetate, parallel group, and multicenter. Patients were randomly assigned to receive anastrozole, 1 mg (n Å 128); anastrozole, 10 mg (n Å 130); or
Medical University of BACKGROUND. This report presents the results of a survival update based on the combined data from two studies that compared the efficacy and tolerability of anastrozole (1 or 10 mg once daily), a selective, nonsteroidal aromatase inhibitor administered orally, and megestrol ace