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3-[(6-Arylamino)pyridazinylamino]benzoic acids: design, synthesis and in vitro evaluation of anticancer activity

โœ Scribed by Abouzid, Khaled A. M.; Khalil, Nadia A.; Ahmed, Eman M.; Mohamed, Khaled Omar


Book ID
120431241
Publisher
Springer
Year
2013
Tongue
English
Weight
526 KB
Volume
36
Category
Article
ISSN
0253-6269

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A simple and highly efficient method has been developed for the synthesis of 3,3-diindolyl oxyindoles by the reaction of indoles with isatin or 5-fluoro isatin using a catalytic amount (5 mol%) of FeCl(3) at room temperature in a short reaction time in high yields. All these compounds were evaluated