3-[5-(4-Fluorophenyl)-1,3,4-thiadiazol-2-yl]-2-phenylthiazolidin-4-one
✍ Scribed by Wan, Rong ;Wu, Feng ;Yin, Jun ;Wang, Jin-Tang
- Publisher
- International Union of Crystallography
- Year
- 2006
- Tongue
- English
- Weight
- 163 KB
- Volume
- 62
- Category
- Article
- ISSN
- 1600-5368
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The title compound, C 18 H 12 F 3 N 3 OS 2 , was synthesized by the reaction of [(Z)-1-phenylmethylidene]{5-[3-(trifluoromethyl)phenyl]-1,3,4-thiadiazol-2-yl}amine and mercaptoacetic acid. In the structure there are intramolecular C-HÁ Á ÁS and C-HÁ Á ÁN and intermolecular C-HÁ Á ÁN hydrogen bonds.
In the title compound, C 18 H 14 ClN 3 O 2 S 2 , the thiazolidine ring adopts an envelope conformation. There are intermolecular C-HÁ Á ÁO interactions, forming centrosymmetric dimers.
In the title compound, C~15~H~12~ClNOS, the thiazolidine ring adopts a twist conformation, with the S and adjacent C (bearing chlorophenyl) atom deviating by −0.140 (1) and 0.158 (2) Å, respectively, from the plane through the other three ring atoms.
In the title molecule, C 22 H 19 NO 2 S, the thiazolidinone ring exhibits a flattened envelope conformation. The methoxyphenyl and biphenyl substituents are in pseudo-equatorial and pseudo-axial orientations, respectively, with respect to the thiazolidinone ring.