✦ LIBER ✦

(2RS)-3-(4-Hydroxyphenyl)-2-(1-oxo-1H-2,3-dihydroisoindol-2-yl)propanoic acid monohydrate

✍ Scribed by Gallagher, John F. ;Brady, Fiona

Publisher: International Union of Crystallography
Year: 2007
Tongue: English
Weight: 722 KB
Volume: 63
Category: Article
ISSN: 1600-5368
DOI: 10.1107/s1600536807014158

No coin nor oath required. For personal study only.

✦ Synopsis

The title compound, C 17 H 15 NO 4 ÁH 2 O, derived from dltyrosine crystallizes as an unusual hydrogen-bonded acidmonohydrate dimer. The asymmetric unit contains two organic molecules and two water molecules. Dimers link through (aryl)O-HÁ Á ÁO C hydrogen bonds along the [101] direction, forming a one-dimensional chain of rings, and further associated via inversion centres (forming a chain of rings aligned in the opposite direction) generating columns. Ruffled sheets arise from interlocking of isoindole rings via -(arene) stacking and C-HÁ Á Á(arene) interactions; C-HÁ Á ÁO interactions generate a three-dimensional network.

📜 SIMILAR VOLUMES

Intermolecular hydrogen bonding in (2S)-

Intermolecular hydrogen bonding in (2S)-2-(1-oxo-1H-2,3-dihydroisoindol-2-yl)propanoic acid

✍ Gallagher, John F. ;Murphy, Carol 📂 Article 📅 2001 🏛 International Union of Crystallography 🌐 English ⚖ 239 KB

The title compound, C 11 H 11 NO 3 , a condensation product of lalanine and ortho-phthalaldehyde, crystallizes in space group P2 1 2 1 2 1 . Intermolecular OÐHÁ Á ÁO C and CÐHÁ Á ÁO hydrogen bonds are present with OÁ Á ÁO and CÁ Á ÁO distances of 2.623 (3) and 3.338 (4) A Ê , respectively.

(2S)-4-Methyl-2-(1-oxo-1H-2,3-dihydrois

(2S)-4-Methyl-2-(1-oxo-1H-2,3-dihydroisoindol-2-yl)pentanoic acid

✍ Brady, Fiona ;Gallagher, John F. 📂 Article 📅 2006 🏛 International Union of Crystallography 🌐 English ⚖ 408 KB

The title compound, C 14 H 17 NO 3 , exhibits carboxylic acid group disorder about the C-CO 2 axis, with site occupancies of 0.79 (5):0.21 (5). Molecules are linked by intermolecular O-HÁ Á ÁO C iso , C-HÁ Á ÁO C iso and C-HÁ Á Á(arene) interactions (iso = isoindolinone).

3-(1H-Indol-3-yl)-2-(2-methylacryloyl)pr

3-(1H-Indol-3-yl)-2-(2-methylacryloyl)propanoic acid

✍ Lv, Zhi-Fang ;Gao, Xiao-Feng ;Wang, Jin-Tang 📂 Article 📅 2007 🏛 International Union of Crystallography 🌐 English ⚖ 167 KB

In the crystal structure of the title compound, C 15 H 16 N 2 O 3 , N-HÁ Á ÁO and O-HÁ Á ÁO hydrogen bonds link the molecules into a three-dimensional network, in which they may be effective in the stabilization of the crystal structure.

(S)-2-(1,3-Dioxoisoindolin-2-yl)propanoi

(S)-2-(1,3-Dioxoisoindolin-2-yl)propanoic acid

✍ Li, Jian ;Liang, Zu-Pei 📂 Article 📅 2006 🏛 International Union of Crystallography 🌐 English ⚖ 216 KB

The title compound, C 11 H 9 NO 4 , was synthesized by mixing phthalic anhydride and (S)-2-aminopropanoic acid in acetic acid. The dihedral angle between the phthalimide ring system and the O3/O4/C9/C11 plane is 86.7 (3) . The crystal structure is stabilized by weak O-HÁ Á ÁO hydrogen bonds.

(3RS,4RS)-3-(2-Furyl)-2-phenethyl-4-(py

(3RS,4RS)-3-(2-Furyl)-2-phenethyl-4-(pyrrolidin-1-ylcarbonyl)-3,4-dihydroisoquinolin-1(2H)-one

✍ Petrova, Rosica ;Shivachev, Boris ;Kosev, Krasimir ;Stoyanova, Malinka ;Angelova 📂 Article 📅 2005 🏛 International Union of Crystallography 🌐 English ⚖ 206 KB

2-, 3-, and 4-(1-Oxo-1H-2,3-dihydroisoin

2-, 3-, and 4-(1-Oxo-1H-2,3-dihydroisoindol-2-yl)benzoic acids and their corresponding organotin carboxylates: Synthesis, characterization, fluorescent, and biological activities

✍ Shuang-Lian Cai; Yong Chen; Wen-Xia Sun; Hui Li; Yun Chen; Shi-Shan Yuan 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 165 KB

Three novel organotin complexes with general formula Sn(OH)(bz)(2)L (bz = benzyl, HL = 2-, 3-, or 4-(1-oxo-1H-2,3-dihydroisoindol-2-yl)benzoic acid) and one of their ligands were prepared and characterized. In vitro antifungal and antibacterial activities of these complexes and ligands were investig