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2B4 functions as a co-receptor in human NK cell activation

✍ Scribed by Simona Sivori; Silvia Parolini; Michela Falco; Emanuela Marcenaro; Roberto Biassoni; Cristina Bottino; Lorenzo Moretta; Alessandro Moretta


Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
108 KB
Volume
30
Category
Article
ISSN
0014-2980

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## Abstract The adapter protein SAP is important for the signal transduction of the family of SLAM‐related receptors (SRR), which have important immune‐modulating functions. The importance of SAP and SRR for a functional immune reaction becomes obvious in patients suffering from X‐linked lymphoprol