𝔖 Bobbio Scriptorium
✦   LIBER   ✦

298 The role of translational research in the design of phase I clinical trials

Book ID
119515776
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
116 KB
Volume
73
Category
Article
ISSN
0167-8140

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In this communication we study the statistical properties of a widely used method for Phase I clinical trials. The designs typically applied in this context are derived from ΓΏxed sample versions of the Up and Down scheme deΓΏned by . Earlier investigations such as those by and concentrate mainly on