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[293] INTERFERON-GAMMA AUGMENTS CHEMICALLY INDUCED APOPTOSIS IN PRIMARY HEPATOCYTES BY INDUCING p53 ACCUMULATION

✍ Scribed by J. Schrader; S. Liith; S. Zander; A.W. Lohse


Book ID
117375392
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
276 KB
Volume
46
Category
Article
ISSN
0168-8278

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The tumor suppressor p53 plays a central role in negative growth control, including growth arrest and apoptosis. Interferons (IFNs) are capable of modulating a variety of cellular responses, including apoptosis. In this study, we have evaluated the influence of y-and a-interferon (IFN) on wild-type