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291. - Uncoupling of CNS serotonin and norepinephrine systems in depression

✍ Scribed by T.D. Geracioti; P. Loosen; N. Ekhator; D. Schmidt; D. Baker; N. Richtand; J. Kascow; P. Keck; M. Ebert

Book ID: 118858375
Publisher: Elsevier Science
Year: 1996
Tongue: English
Weight: 277 KB
Volume: 39
Category: Article
ISSN: 0006-3223
DOI: 10.1016/0006-3223(96)84236-3

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## We used the technique of continuous cerebrospinal fluid (CSF) sampling to test the following hypotheses regarding CNS monoaminergic systems in depression: (1) absolute concentrations of the informational substances tryptophan and 5hydroxyindoleacetic acid (5-HIAA) are altered in the CNS of depres