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282 Regulation of MCL-1 in primary human hepatocytes and hepatoma cells


Book ID
117373794
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
128 KB
Volume
42
Category
Article
ISSN
0168-8278

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CD95 (APO-1/Fas)-mediated apoptosis of hepatocytes plays a central role in the pathophysiology of various human liver diseases. Hepatocyte growth factor (HGF) was shown to exert antiapoptotic functions in rodent hepatocytes. We previously showed that primary human hepatocytes (PHH) are a valuable to