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28 Kinase bypass: A new strategy for antl-HIV drug design

โœ Scribed by C. McGuigan; D. Kinchington; M.F. Wang; S.R. Nicholls; C. Nickson; S. Galpin; D.J. Jeffries; T.J. O'Connor


Book ID
118393097
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
51 KB
Volume
20
Category
Article
ISSN
0166-3542

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## Abstract To test the anticorrelated relationship that was recently displayed in conventional molecular dynamics (MD) simulations, several different restrained MD simulations on a wild type and on the V82F/I84V drugโ€resistant mutant of HIVโ€1 protease were performed. This anticorrelated relationsh