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28 Basal and TNF-alpha stimulated production of PAI-1 by human adipose tissue in culture

✍ Scribed by G. Agostino; M. Tonoli; L. Borgato; B. Deorsola; G. De Sandre; F. Manzato; M. Chilosi; C. Lunardi; M. Cigolini

Book ID
119436866
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
158 KB
Volume
130
Category
Article
ISSN
0021-9150

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Human bone marrow stromal cells repond to stimulation by the monokines IL-1 and TNF by producing colony-stimulating factors such as GM-CSF and G-CSF. In this study we show that I L -l a and TNFa act synergistically to stimulate GM-CSF and G-CSF production by cultured marrow stromal cells. We further