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277 Combination of irinotecan and capecitabine as first line treatment in advanced colorectal cancer (ACC): results of a phase II multicenter trial

✍ Scribed by C.J.A. Punt; J.W.R. Nortier; W.W. ten Bokkel Huinink; S. Falk; D.J. Richel; T. Maughan; G. Groenewegen; J.M. Smith; J.M. Bakker; D.W. Rea


Book ID
118620452
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
168 KB
Volume
1
Category
Article
ISSN
1359-6349

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## Abstract ## BACKGROUND The aim of the current randomized Phase II study was to investigate the efficacy and safety of capecitabine combined with irinotecan as first‐line treatment in metastatic colorectal carcinoma (CRC). ## METHODS A total of 140 patients received capecitabine at a dose of 1