271 Phase II Study of Thalidomide, interleukin-2 (IL-2), and granulocyte macrophage-colony stimulating factor (GM-CSF) in patients with metastatic renal cell carcinoma (RCC)
β Scribed by R. Amato; J. Brown; A. Rawat
- Book ID
- 118621454
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 147 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1359-6349
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## BACKGROUND. Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a cytokine that is involved in the differentiation and proliferation of various hematopoietic precursors. It also has been reported to enhance the antitumor activity of various mature effector cells. Previous reports have
The aim of this study was to determine the response rates and toxicity of two regimens containing granulocyte-macrophage-colony stimulating factor (GM-CSF) in combination with interleukin-2 (IL-2) in the treatment of patients with metastatic renal cell carcinoma. ## METHODS. Therapy given in the f