𝔖 Bobbio Scriptorium
✦   LIBER   ✦

27 INVITED ALDH1 is a marker of normal and cancer breast stem cells and a predictor of poor clinical outcome

✍ Scribed by G. Dontu; C. Ginestier; M. Wicha

Book ID
118624984
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
59 KB
Volume
5
Category
Article
ISSN
1359-6349

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Loss of trimethylation at lysine 27 of h
Loss of trimethylation at lysine 27 of histone H3 is a predictor of poor outcome in breast, ovarian, and pancreatic cancers
✍ Yongkun Wei; Weiya Xia; Zhihong Zhang; Jinsong Liu; Huamin Wang; Nazmi V. Adsay; πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 238 KB

## Abstract Methylation of lysine 27 on histone H3 (H3K27) by the EZH2 complex is an epigenetic mark that mediates gene silencing. EZH2 is overexpressed in many cancers and correlates with poor prognosis in both breast and prostate cancers. However, the status of H3K27 methylation and its clinical