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26 Expression and regulation of the plasminogen activating system in hepatic stellate cells

โœ Scribed by Gabriella Fibbi; Marco Pucci; Enrica Anichini; Alessandra Zamperini; Cecilia Grappone; Giulia Pellegrini; Stefano Milani; Mario Del Rosso

Book ID
117439403
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
119 KB
Volume
11
Category
Article
ISSN
0268-9499

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The plasminogen-activating system in hep
The plasminogen-activating system in hepatic stellate cells
โœ H Leyland; J Gentry; M J Arthur; R C Benyon ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 669 KB

directly by activating the matrix metalloproteinases (MMPs), Urokinase plasminogen activator (uPA) generates interstitial collagenase, and stromelysin. 4,5 Between them plasmin, a process inhibited by plasminogen-activator these enzymes are capable of degrading most matrix compoinhibitor (PAI)-1 and