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246 PAI-1 4G/5G polymorphism and deep venous thrombosis in factor V Leiden patients

Book ID
117439842
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
44 KB
Volume
12
Category
Article
ISSN
0268-9499

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A case control study of deep venous thro
A case control study of deep venous thrombosis in relation to factor V G1691A (Leiden) and A4070G (HR2 Haplotype) polymorphisms
โœ Lobna Bouaziz-Borgi; Philipe Nguyen; Nathalie Hezard; Umayya Musharrafieh; Wassi ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 134 KB

Activated protein C resistance (APCR) is a significant risk factor for venous thromboembolism (VTE), with the factor V (FV) G1691A (Leiden) mutation accounting for the majority of inherited APCR cases. An additional FV polymorphism, A4074G (FV-HR2), reportedly increased VTE risk by some, but not all