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246 Organization of the ribosomal DNA cistrons (rDNA) in patients with Alzheimer's disease

✍ Scribed by S.L.M. Payno; M. de A.C. Smith; L.M.F. Winter; P.H.F. Bertolucci


Book ID
118577943
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
148 KB
Volume
17
Category
Article
ISSN
0197-4580

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## Abstract We developed a novel quantitative assay to test the hypothesis that defects in DNA cytosine methylation might be responsible for the brain chromatin abnormalities and transcriptional alterations observed in patients with Alzheimer's disease (AD). We found no significant difference in pe