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2,4,5- triarylimidazole inhibitors of IL-1 biosynthesis

✍ Scribed by Timothy F. Gallagher; Susan M. Fier-Thompson; Ravi.S. Garigipati; Margaret E. Sorenson; Juanita M. Smietana; Dennis Lee; Paul E. Bender; John C. Lee; Jeffrey T. Laydon; Don E. Griswold; Marie C. Chabot-Fletcher; John J. Breton; Jerry L. Adams


Book ID
103982948
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
316 KB
Volume
5
Category
Article
ISSN
0960-894X

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## Abstract magnified image Lophine hydroperoxides underwent base‐triggered 1,5‐phenyl migration in DMSO to afford imidazolones in high yields, instead of amidines with chemiluminescence (CL). The corresponding imidazolols were believed to intermediates and they were successfully obtained by treati