2.445 A summary of the in vitro pharmacology of pardoprunox (SLV308): A novel dopamine D2/D3 partial agonist and 5-HT1A agonist for the treatment of Parkinson's disease
β Scribed by A. McCreary; J. Glennon; J.-H. Reinders; M. Hesselink; G. van Scharrenburg
- Book ID
- 117753005
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 63 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1353-8020
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract This study examined the efficacy and safety of the partial dopamine agonist, pardoprunox (SLV308), in the treatment of patients with early Parkinson's disease (PD). Patients were randomized to receive pardoprunox (n = 69) or placebo (n = 70). Pardoprunox was titrated to each patient's o
Herein, we evaluate the interaction of the β£ 2 -AR antagonist, yohimbine, as compared to fluparoxan, at multiple monoaminergic receptors and examine their roles in the modulation of adrenergic, dopaminergic and serotonergic transmission in freelymoving rats. Yohimbine displays marked affinity at hum