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242 PHOSPHATE AND CALCIUM INFLUX ARE REQUIRED FOR TGFβ-MEDIATED STIMULATION OF ANK (progressive ankylosis) EXPRESSION AND PPi TRANSPORT FUNCTION DURING CHONDROGENESIS

✍ Scribed by P. Oca; R. Zaka; A.S. Dion; C.J. Williams


Book ID
114351453
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
59 KB
Volume
17
Category
Article
ISSN
1063-4584

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Phosphate and calcium are required for T
✍ Paulina Oca; Raihana Zaka; Arnold S. Dion; Theresa A. Freeman; Charlene J. Willi 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 353 KB

## Abstract The expression of ANK, a key player in biomineralization, is stimulated by treatment with TGFβ. The purpose of this study was to determine whether TGFβ stimulation of ANK expression during chondrogenesis was dependent upon the influx of calcium and phosphate into cells. Treatment of ATD