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2′,4′-Dihydroxychalcone-induced apoptosis of human gastric cancer MGC-803 cells via down-regulation of survivin mRNA

✍ Scribed by Chenghua Lou; Guangming Yang; Hao Cai; Mingchang Zou; Zisheng Xu; Yu Li; Fengming Zhao; Weidong Li; Li Tong; Mingyan Wang; Baochang Cai

Book ID: 116920265
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 360 KB
Volume: 24
Category: Article
ISSN: 0887-2333
DOI: 10.1016/j.tiv.2010.05.003

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## Abstract The prostate‐apoptosis‐response‐gene‐4 (Par‐4) protein has been shown to function as an effector of cell death in response to various apoptotic stimuli that trigger mitochondria and membrane receptor‐mediated cell death pathways. We found that overexpressing Par‐4 by stable transfection