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2,4-Diaminopyrido[3,2-d]pyrimidine Inhibitors of Dihydrofolate Reductase from Pneumocystis carinii and Toxoplasma gondii

✍ Scribed by Rosowsky, Andre; Forsch, Ronald A.; Queener, Sherry F.


Book ID
127151290
Publisher
American Chemical Society
Year
1995
Tongue
English
Weight
909 KB
Volume
38
Category
Article
ISSN
0022-2623

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Synthesis of 2,4-diaminopyrido[2,3-d]pyr
✍ Andre Rosowsky; Hongning Fu; Sherry F. Queener πŸ“‚ Article πŸ“… 2000 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 560 KB

## Abstract The synthesis of four previously undescribed 2,4‐diaminopyrido[2,3‐__d__]pyrimidines (**3,4**) and 2,4‐diaminoquinazolines (**5,6**) with a bulky tricyclic aromatic group at the 6‐position is described. Condensation of dibenz[__b,f__]azepine with 2,4‐diamino‐6‐bromomethylpyrido[2,3‐__d_